Study to Evaluate the Safety, Phage Kinetics, and Efficacy of Inhaled AP-PA02 in Subjects With Non-Cystic Fibrosis Bronchiectasis and Chronic Pulmonary Pseudomonas Aeruginosa Infection

Completed · Phase 2 · Has a placebo group

Conditions studied: Non-cystic Fibrosis Bronchiectasis, Pseudomonas Aeruginosa, Lung Infection

In brief

A phase 2, multi-center, double-blind, randomized, placebo-controlled study to evaluate the safety, phage kinetics, and efficacy of inhaled AP-PA02 administered in subjects with non-cystic fibrosis bronchiectasis and chronic pulmonary Pseudomonas aeruginosa infection.

Key facts

Study ID

NCT05616221

Run by

Armata Pharmaceuticals, Inc.

People needed

48

Starts

2023-01-10

Expected to finish

2024-08-08

Last updated by the study team

2026-01-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• New York Medical College — Hawthorne, New York, United States
• Velocity Clinical Research — Mobile, Alabama, United States
• Southern California Institute for Respiratory Diseases Cedars-Sinai West Tower — Los Angeles, California, United States
• UCONN Health — Farmington, Connecticut, United States
• Georgetown University Hospital / Pulmonary Critical Care and Sleep Medicine — Washington D.C., District of Columbia, United States
• Southwest General Healthcare Center — Fort Myers, Florida, United States
• TecTum Medical Research, Inc. — Hollywood, Florida, United States
• Mayo Clinic/Pulmonary, Critical Care, and Sleep Medicine — Jacksonville, Florida, United States
• University of Miami — Miami, Florida, United States
• St. Lukes Hospital — Boise, Idaho, United States
• The University of Kansas Medical Center / Dept of Medicine — Kansas City, Kansas, United States
• Johns Hopkins University School of Medicine — Baltimore, Maryland, United States
• Mayo Clinic — Rochester, Minnesota, United States
• University of Cincinnati - College of Medicine — Cincinnati, Ohio, United States
• Rutgers Robert Wood Johnson Medical School — New Brunswick, New Jersey, United States
• University Hospitals of Cleveland Medical Center — Cleveland, Ohio, United States
• Oregon Health & Science University — Portland, Oregon, United States
• University of Pennslyvania — Philadelphia, Pennsylvania, United States
• Medical University of South Carolina — Charleston, South Carolina, United States
• Vanderbilt University Medical Center — Nashville, Tennessee, United States
• University of Texas Health Science Center at Tyler — Tyler, Texas, United States
• Virginia Commonwealth University (VCU) — Richmond, Virginia, United States
• University of Washington Medical Center — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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