Confounding Factors of Chronic Endometritis in Women With Reproductive Failure
Recruiting now
Conditions studied: IVF
In brief
The aim of the study is to investigate the confounding factors of chronic endometritis and therapeutic benefits of antibodies targeting plasma cells in women with reproductive failure.
Key facts
- Study ID
- NCT05613049
- Run by
- Chinese University of Hong Kong
- People needed
- 720
- Starts
- 2023-01-26
- Expected to finish
- 2028-01-31
- Last updated by the study team
- 2025-03-27
Who can join
Age: 20 and older, up to 45. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Age 20-45 years;
- Women with a history of 2 or more consecutive miscarriages before 24 weeks of gestation12; or
- Women who failed to conceive after unprotected intercourse for one year; or
- Women who failed failure to achieve a clinical pregnancy after two consecutive cycles of IVF, ICSI or frozen embryo replacement cycles where the cumulative number of transferred embryos is no less than four for day-2 embryos and no less than 2 for day-5 embryos (blastocysts), with all embryos being of good quality.
You may not qualify if…
- Uncorrected uterine anomalies, such as the septate or bicornuate uterus, fibroids (submucous/intramural);
- Untreated hydrosalpinx;
- History of antiphospholipid syndrome;
- Known clinical autoimmune disease;
- Undergoing immunotherapy;
- Abnormal thyroid function;
- Abnormal karyotyping.
- Those with active pelvic inflammatory disease or suspicion of infection etc.
Where it is running
- The Chinese University of Hong Kong — Hong Kong, Hong Kong (enrolling)
Full record on ClinicalTrials.gov
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