Renal Nerve Denervation(RDN) and Renal Function

Recruiting now

Conditions studied: Effects of RDN on Renal Function

In brief

Current studies have found the efficacy of RDN in the treatment of hypertension, however, the safety of RDN in renal function is still lacking. Therefore, the investigators are aimed to study the effect of RDN on renal function.

Key facts

Study ID

NCT05612906

Run by

Zhengrong Huang

People needed

50

Starts

2022-06-01

Expected to finish

2026-12-01

Last updated by the study team

2025-02-27

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18<age≤75 years; 2.clinic blood pressure ≥ 140/90 mmHg or 24-hour ambulatory blood pressure monitoring average blood pressure ≥ 135/85 mmHg after taking 3 or more antihypertensive drugs for more than 4 weeks; 3.essential hypertension, renal parenchymal hypertension, or hypertension patients who are willing to receive RDN ; 4.who signed informed consent and were approved by the Ethics Committee of the First Affiliated Hospital of Xiamen University.

You may not qualify if…

• pregnant women or lactating patients;
• identified secondary hypertension or Pseudo hypertension;
• whose renal arteries were unsuitable for ablation
• obvious bleeding tendency and blood system diseases;
• malignant tumors or end-stage diseases; ⑥Severe peripheral vascular disease, abdominal aortic aneurysm; ⑦A history of the acute coronary syndrome within two weeks; ⑧acute or severe systemic infection; ⑨drug or alcohol dependence or refusal to sign informed consent.

Where it is running

• zhengrong Huang — Xiamen, Fujian, China (enrolling)

Full record on ClinicalTrials.gov

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