Improve Outcomes for Older Allogeneic Transplant Recipients

Recruiting now · Not applicable

Conditions studied: Allogeneic Transplantation

In brief

This is an interventional pilot study to determine whether implementation of a supervised exercise program can improve outcomes in subjects undergoing allogeneic HCT. The primary objective is to determine feasibility. Up to 60-72 evaluable subjects will be enrolled. Evaluable subjects are defined as those participating in the exercise intervention.

Key facts

Study ID

NCT05612789

Run by

Abramson Cancer Center at Penn Medicine

People needed

72

Starts

2023-02-15

Expected to finish

2031-06-01

Last updated by the study team

2025-12-10

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Cohort A (Prehab)
• Age 60 years or older.
• Planned allogeneic HCT in the next 1-6 months.
• Hematological malignancy as the indication for HCT.
• Pre-frail or frail by Fried frailty phenotype.
• Cohort B (Rehab)
• Age 60 years or older.
• Planned allogeneic HCT or HCT within the last 30 days.
• Hematological malignancy as the indication for HCT.

You may not qualify if…

• Cohorts A and B
• Comorbid disability or illness that prevents safe exercise.

Where it is running

• Penn Medicine — Philadelphia, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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