Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors

Recruiting now

Conditions studied: Testicular Cancer, Survivorship, ASCVD, Coronary Artery Disease, Lipid Disorder, Hypogonadism, Male, Cisplatin Adverse Reaction, Bone Marrow Transplant Complications

In brief

Late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin-based chemotherapy and bone marrow transplant

Key facts

Study ID

NCT05611307

Run by

Indiana University

People needed

150

Starts

2022-10-11

Expected to finish

2027-08-01

Last updated by the study team

2026-07-27

Who can join

Age: 18 and older, up to 99. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Patients >18 years of age
• Patients will be recruited only if cancer-free at clinical evaluation time.
• For the cases a confirmed TC diagnosis who received one or more cycles of CBCT-based chemotherapies (CBCT group, Arm 2)
• For the cases with a confirmed TC diagnosis who received one or more cycles of CBCT-based chemotherapies and underwent BMT for relapsed refractory disease (CBCT \& BMT group, Arm 3).
• For the comparison cohort, biopsy-proven TC patients who had surgery for or surveillance of their testicular cancer and never received CBCTCBCT or BMT (surgical/surveillance, Arm 1)

You may not qualify if…

• Prior known myocardial infarction (MI), atherosclerotic cardiovascular disease (ASCVD)
• Significant renal disease (GFR<40)
• Allergy to iodinated contrast
• Antecedent chemotherapy for another primary cancer.

Where it is running

• Indiana University — Indianapolis, Indiana, United States (enrolling)

Full record on ClinicalTrials.gov

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