Imaging Intravenous Iron

Recruiting now

Conditions studied: Iron-deficiency

In brief

The aim of this study is to track where the iron goes in different tissues in the hours, days and weeks after an intravenous iron infusion. We will track iron in tissues using MRI relaxometry parameters R1/R2/R2\* which are well established as accurate indicators of tissue iron content.

Key facts

Study ID

NCT05609318

Run by

University of Oxford

People needed

12

Starts

2022-10-29

Expected to finish

2026-12-31

Last updated by the study team

2026-05-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participant is willing and able to give informed consent for participation in the study.
• Aged 18 years or above.
• Anaemia (haemoglobin less than 120g/L for women and less than 130g/L for men) and/or confirmed iron deficiency (ferritin less than 100mcg/L and/or transferrin saturation less than 20%).
• Scheduled to receive intravenous iron for correction of iron deficiency.

You may not qualify if…

• Any MRI incompatible implants (e.g. cardiac, neuro, ocular implants, surgical clips, aneurysm clips, shrapnel/bullets)
• Pregnant or lactating participant
• Acute decompensated heart failure
• Unstable clinical status
• Any other medical conditions which would influence the reliability of the study results determined by the investigators.
• Any other contraindication to MRI to be confirmed by the qualified MRI operator, e.g. tattoos containing traces of metal.

Where it is running

• Oxford Centre for Clinical Magnetic Resonance Research (OCMR) — Oxford, Oxfordshire, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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