Complementary Investigation of Perfusion and Anatomy Measures of the Heart With MRI and Combined PET/MRI

Recruiting now

Conditions studied: Coronary Artery Disease

In brief

The goal of this observational study is to evaluate the complimentary information of anatomy, perfusion and viability of PET and MR. The main question\[s\] it aims to answer are: * to compare perfusion and anatomy measurements and perfusion related signals from PET and MR imaging and estimate its prognostic values. * to evaluate potential optimization of routine scanning procedure with regards to completeness and potential added value of quantitative measurements.

Key facts

Study ID

NCT05609214

Run by

University of Zurich

People needed

200

Starts

2022-11-21

Expected to finish

2026-12-01

Last updated by the study team

2023-12-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male and Female participants over the age of 18 years
• Written informed consent by the participant after information about the research project
• Symptoms consistent with possible coronary artery disease
• Clinical referral for a vasodilator stress CMR and/or PET examination

You may not qualify if…

• Patients with high degree heart block
• Contraindications to gadolinium-enhanced CMR examination
• Severe claustrophobia
• Specific implantable devices which are contraindicated for CMR
• Current pregnancy
• Advanced renal disease (GFR<30)
• Uncontrolled obstructive pulmonary disease or asthma
• Atrial fibrillation at the time of study enrolment

Where it is running

• University Hospital Zurich — Zurich, Switzerland (enrolling)

Full record on ClinicalTrials.gov

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