Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma
Running, not enrolling · Phase 3
Conditions studied: High-risk Large B-cell Lymphoma (LBCL)
In brief
The goal of this clinical study is to compare the study drug, axicabtagene ciloleucel, versus standard of care (SOC) in first-line therapy in participants with high-risk large B-cell lymphoma.
Key facts
- Study ID
- NCT05605899
- Run by
- Kite, A Gilead Company
- People needed
- 300
- Starts
- 2023-02-10
- Expected to finish
- 2031-03-01
- Last updated by the study team
- 2026-04-15
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Banner MD Anderson Cancer Center — Gilbert, Arizona, United States
- Mayo Clinic — Phoenix, Arizona, United States
- UC San Diego Moores Cancer Center — La Jolla, California, United States
- University of California Los Angeles (UCLA) — Los Angeles, California, United States
- Colorado Blood Cancer Institute — Denver, Colorado, United States
- Moffitt Cancer Center — Tampa, Florida, United States
- Georgia Cancer Center at Augusta University — Augusta, Georgia, United States
- Northwestern Memorial Hospital — Chicago, Illinois, United States
- University of Chicago Medical Center — Chicago, Illinois, United States
- University of Iowa — Iowa City, Iowa, United States
- The University of Kansas Hospital — Westwood, Kansas, United States
- Norton Cancer Institute, St. Matthews Campus — Shelbyville, Kentucky, United States
- Ochsner Clinic Foundation — New Orleans, Louisiana, United States
- University of MD Greenebaum Comprehensive Cancer Center — Baltimore, Maryland, United States
- Dana-Farber Cancer Institute — Boston, Massachusetts, United States
- University of Michigan — Ann Arbor, Michigan, United States
- Mayo Clinic Cancer Center Outpatient Pharmacy — Rochester, Minnesota, United States
- John Theurer Cancer Center at Hackensack University Medical Center — Hackensack, New Jersey, United States
- Roswell Park Cancer Institute — Buffalo, New York, United States
- Weill Cornell Medical College - NewYork Presbyterian Hospital — New York, New York, United States
- Columbia University Medical Center — New York, New York, United States
- University of Rochester Medical Center — Rochester, New York, United States
- Montefiore Medical Center — The Bronx, New York, United States
- Novant Health Cancer Institute- Hematology — Charlotte, North Carolina, United States
- University of Alabama Hospital — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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