Reality-monitoring & Stress
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Healthy Participants
In brief
Reality-monitoring is a crucial cognitive process in daily life to remember the source of an information. Deficits of reality-monitoring have been shown into the continuum of schizophrenia, suggesting a preexisting alteration in population at-risk for psychosis that will be exacerbated during psychotic transition. It is admitted that stress plays a crucial role in the psychotic transition and can alter cognitive performances. However, less is known about the effects of stress on reality-monitoring, even though this process appears to be central in psychotic disorders. The aim of this project is to investigate the effect of stress on reality-monitoring, both on behavioral and neurophysiological aspects
Key facts
- Study ID
- NCT05595434
- Run by
- Hôpital le Vinatier
- People needed
- 40
- Starts
- 2024-04-25
- Expected to finish
- 2025-11-16
- Last updated by the study team
- 2025-07-24
Who can join
Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Right-handed Men and Women aged between 18 and 30
- Having given their written informed consent
- For women: oral contraceptive use
- French speakers and readers
You may not qualify if…
- Do not consent to be included in the study
- Smokers
- Night workers
- Having visual or hearing impairments that could prevent the successful completion of tasks involving reading or listening to sounds
- Taking drug treatment (except oral contraceptive)
- Having a somatic pathology in particular neurological, endocrinal or blood circulation diseases (e.g., Raynaud's disease)
- Having personal or first-degree relatives' history of diagnosed psychiatric disorders (according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders - DSM5)
- Having psychotic prodomes measured by a score above 6 in the "prodomal questionnaire' - PQ-16 (Ising et al., 2012)
- Having developed musical abilities (that is, regularly practicing a musical instrument)
- Being pregnant or nursing
Where it is running
- Centre Hospitalier le Vinatier — Bron, France (enrolling)
Full record on ClinicalTrials.gov
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