Cherries Role in Gut Microbiota-liver-brain Function

Completed · Phase 1 · Has a placebo group

Conditions studied: Obesity

In brief

Sweet cherries (Prunus avium) are a good source of bioactive compounds including dietary fiber and phytochemicals which have been credited with multiple health benefits, including anti-inflammatory and antioxidant properties as well as preventing obesity-related metabolic disorders. However, most studies have shown such benefits using in vitro or animal models. The aim of this study was to examine the influence of DSC consumption on obesity-associated inflammation, metabolic disorders, cognitive impairment, and gut dysbiosis in obese individuals.

Key facts

Study ID

NCT05586386

Run by

Texas A&M University

People needed

60

Starts

2020-02-06

Expected to finish

2021-09-20

Last updated by the study team

2022-10-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or female at least 18 years old;
• No history of chronic diseases or intestinal disorders.
• BMI: ≥ 30 and ≤ 40.

You may not qualify if…

• History of acute cardiac event, stroke, or cancer
• Alcohol or substance abuse within the last 6 months
• Recurrent admittance to the hospital (twice or more)
• Allergy, intolerance, or sensitivity to berries
• Hepatitis (B or C) or HIV
• Smoking more than 1 pack/week
• Liver or renal dysfunction
• Diabetic retinopathy
• History of glaucoma, retinitis pigmentosa, optic neuropathy, retinal vascular occlusions, strabismus, macular degeneration or autoimmune disorders related to visual health
• History of dizziness/fainting during and after blood draws
• Known lactose intolerance, gluten sensitivity, or celiac disease
• Currently on medications/antibiotics
• Pregnancy or lactation (or planned pregnancy)

Where it is running

• Texas A&M University — College Station, Texas, United States

Full record on ClinicalTrials.gov

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