Behavioral Change Following Alzheimer's Disease (AD) Biomarker Disclosure
Completed · Not applicable
Conditions studied: Mild Cognitive Impairment, Alzheimer Disease, Amnestic Mild Cognitive Disorder
In brief
The proposed project will assess long-term changes to health/lifestyle, advanced planning, and research engagement that Black and White patients with Amnestic Mild Cognitive Impairment (aMCI) make following disclosure of positron emission tomography-based amyloid and tau burden and associated risk of conversion to Dementia-Alzheimer's Type. Healthcare access will be explored as potential barrier to or facilitator of behavior change.
Key facts
- Study ID
- NCT05584241
- Run by
- University of Michigan
- People needed
- 102
- Starts
- 2023-02-20
- Expected to finish
- 2026-05-21
- Last updated by the study team
- 2026-07-08
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosed with Amnestic Mild Cognitive Impairment within the past 12 months,
- Available PET Aβ and tau imaging
You may not qualify if…
- Significant neurologic diagnosis (e.g., Alzheimer's dementia or other neurodegenerative dementia, Parkinson's disease, seizure disorder, tumor, multiple sclerosis)
- Neurologic injury (e.g., significant stroke or moderate-severe head injury, defined by loss of consciousness > 5 minutes, presence of significant post-traumatic amnesia, or the need for extended hospitalization or intervention)
- Motor abnormalities indicative of a non-AD etiology
- Severe mental illness (e.g., bipolar disorder, psychosis), moderate-severe mood or anxiety disorder, active substance use disorder (o reduce the likelihood of severe psychological distress, participants must screen negative for moderate-severe depressive or anxiety symptoms at study enrollment.)
- Inability to provide independent informed consent.
Where it is running
- The University of Michigan — Ann Arbor, Michigan, United States
Full record on ClinicalTrials.gov
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