Studying the Effects of Cannabis on Vasculature
Recruiting now
Conditions studied: Cardiovascular Diseases, Inflammation, Atherosclerosis
In brief
Cannabis is commonly used globally. It is associated with psychiatric problems, but the effects on the cardiovascular system are unclear. In this project, the investigators plan to study the effects of cannabis on the cardiovascular system. This will be done by using a non-invasive test to measure blood vessel function and by using blood samples to measure inflammation. As a control for this project, the investigators would like to test the blood vessel function and inflammation levels of participants who do not use cannabis. This study will provide important information on the long term cardiovascular effects of cannabis.
Key facts
- Study ID
- NCT05581368
- Run by
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- People needed
- 100
- Starts
- 2023-12-01
- Expected to finish
- 2025-12-30
- Last updated by the study team
- 2025-06-15
Who can join
Age: 19 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- age: 19 to 80
- males and females
- all ethnicities
- cannabis use at least 3-4 times per week or more in the past 6 months (50 volunteers, experimental group)
- patients who do not use cannabis (50 volunteers, control group)
- no history of cardiovascular disease
You may not qualify if…
- that ingest cannabis containing cannabidiol (CBD)
- that are unable to provide a receipt for the cannabis product(s) they ingest
- that are unwilling to stop consuming soy products and/or genistein 48 hours prior to appointments.
Where it is running
- London Regional Health Science Centre — London, Ontario, Canada (enrolling)
Full record on ClinicalTrials.gov
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