Effective Translation of Endovascular Thrombectomy Trials Into Real-world Practice in the Asia-Pacific
Recruiting now
Conditions studied: Ischemic Stroke, Stroke, Stroke, Acute, Stroke, Ischemic, Brain Diseases, Major Adverse Cardiovascular Event
In brief
As a major breakthrough of acute stroke treatment over the past decade, endovascular thrombectomy (EVT) drastically improved neurological recovery and survival in patients with large vessel occlusion (LVO) ischemic strokes in major clinical trials. Nevertheless, much remained uncertain about the implementation of scientific evidence of EVT into real-world benefits. For instance, healthcare policies that influence critical time-matrices, endovascular thrombectomy techniques that may enhance success rate or prevent complications, or advanced imaging techniques that allow precise prognosis or expansion of treatment populations, should be evaluated. On the other hand, capturing LVO patients who were not able to undergo EVT may reveal the gap between clinical trials and real-world practice in the Asia-Pacific. In this multicenter prospective collaboration across the Asian-Pacific, the investigators aim to evaluate the determinants of effective EVT in the real-world setting.
Key facts
- Study ID
- NCT05578300
- Run by
- Chinese University of Hong Kong
- People needed
- 350
- Starts
- 2022-10-21
- Expected to finish
- 2032-12-31
- Last updated by the study team
- 2026-03-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patient who are over 18 years of age.
- Patient with ischemic stroke with suspected large vessel occlusion (LVO), defined as occlusion of the internal carotid artery (ICA), M1 or M2 segment of the middle cerebral artery (MCA), or basilar artery (BA).
You may not qualify if…
- Patient with isolated vertebral artery occlusion not involving the BA.
Where it is running
- Linyi People's Hospital — Linyi, Shandong, China (enrolling)
- The Affiliated Hospital of Medical College of Qingdao University — Qingdao, Shandong, China (enrolling)
- Chinese University of Hong Kong — Hong Kong, Hong Kong (enrolling)
Full record on ClinicalTrials.gov
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