Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease

Recruiting now · Phase 3

Conditions studied: Parkinson's Disease

In brief

This study aims to investigate the possible efficacy and safety of synbiotic preparation of Lactobacillus acidophilus probiotic with prebiotic fibers as an adjuvant therapy in the treatment of Parkinson's disease

Key facts

Study ID

NCT05576818

Run by

Tanta University

People needed

66

Starts

2022-06-30

Expected to finish

2025-06-01

Last updated by the study team

2025-04-10

Who can join

Age: 45 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age between 45 and 65 years old
• Both sexes
• Patients with Parkinson's disease on dopamine replacement therapy
• Modified Hoehn and Yahr stage, MHY 1-4

You may not qualify if…

• Patients who are currently using or used antibiotics therapy in the preceding month
• Patients who are currently using or used other probiotic products in the preceding two weeks
• Patients scheduled to undergo GIT surgery or those underwent GIT surgery
• Patients with Known allergy to probiotics
• Patients receiving artificial enteral or intravenous nutrition
• Patients with depression and/or psychosis
• Patients taking antioxidant and/or anti-inflammatory medications
• Patients with Hyperthyroidism
• Patients with inflammatory condition and/or condition involving oxidative stress
• Smokers
• Modified Hoehn \& Yahr stage MHY 5

Where it is running

• Tanta University — Tanta, El Gharbia, Egypt (enrolling)

Full record on ClinicalTrials.gov

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