Protocolized Initiation of Clonidine to Prevent Dexmedetomidine Withdrawal

Completed · Phase 4

Conditions studied: Withdrawal; Therapeutic Substance

In brief

The purpose of this study is to determine if the protocolized use of clonidine will reduce dexmedetomidine withdrawal symptoms, reduce PICU length of stay, and reduce costs related to sedation during hospital admission.

Key facts

Study ID

NCT05575219

Run by

The University of Texas Health Science Center, Houston

People needed

128

Starts

2022-10-08

Expected to finish

2024-02-15

Last updated by the study team

2025-01-28

Who can join

Age: 0 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Dexmedetomidine infusion for greater than or equal to 72 hours

You may not qualify if…

• Admission for head trauma
• Psychiatric history
• Use of alpha-2 agonist medications at home
• Death while on dexmedetomidine

Where it is running

• Children's Memorial Hermann Hospital — Houston, Texas, United States

Full record on ClinicalTrials.gov

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