Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane

Recruiting now

Conditions studied: Acute Kidney Injury Due to Sepsis

In brief

The new adsorbing membrane for continuous renal replacement therapy (CRRT), oXiris, can reduce plasma cytokines and endotoxins in septic shock patients with severe acute kidney injury, compared with standard membranes. However, its hemodynamic stability or benefits have not been thoroughly evaluated although this is reasonable.

Key facts

Study ID

NCT05575024

Run by

Seoul National University Hospital

People needed

98

Starts

2024-01-01

Expected to finish

2026-12-31

Last updated by the study team

2025-05-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged ≥ 18 years
• Sepsis related acute kidney injury requiring continuous renal replacement therapy

You may not qualify if…

• No monitoring of blood pressure and ECG

Where it is running

• Seoul National University Hospital — Seoul, South Korea (enrolling)

Full record on ClinicalTrials.gov

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