NOAC9 - Circulating Tumor DNA Guided Follow-Up in Anal Cancer
Recruiting now · Not applicable
Conditions studied: Anal Cancer
In brief
This study investigates if circulating tumor DNA can improve the detection of early treatment failure or recurrence in localized squamous cell carcinoma of the anus (SCCA) after curative chemoradiotherapy thereby increasing the potential for cure. This will be done by comparing the standard follow-up program with ctDNA guided imaging follow-up. Secondly, the aim is to establish early interventions against late morbidities.
Key facts
- Study ID
- NCT05572801
- Run by
- Aarhus University Hospital
- People needed
- 400
- Starts
- 2023-08-02
- Expected to finish
- 2031-06-01
- Last updated by the study team
- 2024-08-14
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with SCCA eligible for definitive (chemo)radiotherapy
- ≥ 18 of years
- Written and oral consent
You may not qualify if…
- Conditions that will contraindicate blood samples
- Conditions that will contraindicate a PET-CT scan.
- Potential lack of compliance to standard FU program and study participation.
Where it is running
- Department of Oncology Herlev and Gentofte Hospital — Herlev, Capital Region of Denmark, Denmark (enrolling)
- Department of Oncology, Vejle Hospital — Vejle, The Regions of Southern Denmark, Denmark (enrolling)
- Aarhus University Hospital — Aarhus, Denmark (enrolling)
- Tampere University Hospital — Tampere, Finland
- Turku University Hospital — Turku, Finland
- Haukeland University Hospital — Bergen, Norway
- Oslo University Hospital — Oslo, Norway
- University Hospital of North Norway — Tromsø, Norway
- St. Olav's University Hospital — Trondheim, Norway
- Sahlgrenska University Hospital — Gothenburg, Sweden
- Skåne University Hospital Lund — Lund, Sweden
- Karonlinska University Hospital — Stockholm, Sweden
- Norrlands University Hospital — Umeå, Sweden
Full record on ClinicalTrials.gov
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