Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy
Recruiting now · Not applicable
Conditions studied: Cerebral Palsy, Spastic Cerebral Palsy
In brief
12 adults with spastic CP will complete 6 baseline sessions and 24 down conditioning sessions held 3 times/week. All clinical and physiological assessments collected at baseline will be reassessed after study completion, and follow ups after 2 weeks, 1 month and 3 months. The soleus H reflex (electric analogue of the stretch reflex) will be elicited in all sessions. In each session, participants will complete 20 baseline trials and 225 down conditioning trials to decrease the magnitude of the H-Reflex.
Key facts
- Study ID
- NCT05571033
- Run by
- Burke Medical Research Institute
- People needed
- 12
- Starts
- 2022-09-30
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2023-09-26
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age 18 and above
- Diagnosis of spastic Cerebral Palsy
- Gross Motor Function Classification System level I-III
- Stable medical background
- Current medication will remain unchanged for 3 months
- Provides informed consent
- can walk at least 10 meters with or without assistive device
- meets minimum study procedure requirements (elicitation of H-reflex).
You may not qualify if…
- Pregnancy
- uncontrolled diabetes
- weak dorsiflexion
- History of cardiac conditions
- cognitive deficits that interfere with study procedure and steps for completion
- Botox within 2 months of the study
- H/O ankle surgeries in affected leg (Dorsal root rhizotomy etc.)
- regular use of electrical stimulation to lower extremity muscles
- Cochlear or metal implantations on body
- No history of seizure after age 2 years
- Current use of antiseizure medicines
- Any metal or magnetic components in the head (surgical clips, metal work etc.)
- Implanted device or cardiac pacemakers (applicable for DS8R too)
- Skin disorders
- Damaged skin (wounds, broken skin, or recent scar tissue)
- Allergy to latex (tape)
Where it is running
- Burke Neurological Institute — White Plains, New York, United States (enrolling)
Full record on ClinicalTrials.gov
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