Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15
Completed · Phase 2 · Has a placebo group
Conditions studied: Non-small Cell Lung Cancer, Pancreatic Cancer, Colorectal Cancer, Loss of Appetite, Fatigue, Cachexia
In brief
Study to evaluate the efficacy, safety and tolerability of ponsegromab compared to placebo in patients with cancer, cachexia, and elevated GDF 15.
Key facts
- Study ID
- NCT05546476
- Run by
- Pfizer
- People needed
- 187
- Starts
- 2022-11-21
- Expected to finish
- 2025-04-23
- Last updated by the study team
- 2026-06-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- CARTI Cancer Center — Little Rock, Arkansas, United States
- CARTI North Little Rock — North Little Rock, Arkansas, United States
- CARTI Stuttgart — Stuttgart, Arkansas, United States
- Pacific Cancer Medical Center INC — Anaheim, California, United States
- Beverly Hills Cancer Center — Beverly Hills, California, United States
- Emad Ibrahim,MD,INC. — Redlands, California, United States
- Providence Medical Foundation — Santa Rosa, California, United States
- IU Health Arnett Cancer Center — Lafayette, Indiana, United States
- Pennington Biomedical Research Center — Baton Rouge, Louisiana, United States
- Tandem Clinical Research — Marrero, Louisiana, United States
- Bozeman Health Deaconess Hospital — Bozeman, Montana, United States
- Oregon Health and Science University: Center for Health and Healing 1 — Portland, Oregon, United States
- Oregon Health and Science University: Center for Health and Healing 2 — Portland, Oregon, United States
- Oregon Health and Science University — Portland, Oregon, United States
- The University of Texas MD Anderson Cancer Center — Houston, Texas, United States
- Carta - Clinical Associates in Research Therapeutics of America, LLC — San Antonio, Texas, United States
- Virginia Mason Medical Center — Seattle, Washington, United States
- Wenatchee Valley Hospital — Wenatchee, Washington, United States
- St Vincent's Hospital Sydney — Darlinghurst, New South Wales, Australia
- Orange Hospital — Orange, New South Wales, Australia
- Peter MacCallum Cancer Centre — Melbourne, Victoria, Australia
- Western Health-Sunshine & Footscray Hospitals — St Albans, Victoria, Australia
- Complex Oncology Center - Burgas — Burgas, Bulgaria
- Specialized Hospital for Active Treatment of Oncology - Haskovo — Haskovo, Bulgaria
- CARTI Conway — Conway, Arkansas, United States
Full record on ClinicalTrials.gov
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