The Validation and Development of Termination-of-Resuscitation (TOR) Rules in OHCA Patients in Asia Countries
Recruiting now
Conditions studied: Out-Of-Hospital Cardiac Arrest
In brief
Objectives/Hypotheses 1. Prehospital termination-of-resuscitation (TOR) rules were developed in North American and European sites. Whether they remained valid in different geographic, ethnic, and cultural background areas is still under debate. 2. Differences in characteristics of out-of-hospital cardiac arrests (OHCAs) and configurations of emergency medical service (EMS) between the Western and Asian countries, including relatively lower rate of presenting shockable rhythm (i.e. ventricular fibrillation / ventricular tachycardia; VF/VT), lower rates of bystander CPR, less advanced life support (ALS) implementation, and less public access defibrillators, might create potential threats to the prediction accuracy of TOR rules. 3. We aim to conduct a study to validate the performance of ever published TOR rules in Asian OHCA population, including non-traumatic, traumatic, and pediatric OHCA patients. Furthermore, assess the possible variables that may impact the performance of TOR rules. 4. We also aim to develop new TOR rules based on PAROS registry for Asia population, focusing on non-traumatic, traumatic, and pediatric OHCA patients, respectively.
Key facts
- Study ID
- NCT05545176
- Run by
- National Taiwan University Hospital
- People needed
- 140000
- Starts
- 2007-01-01
- Expected to finish
- 2032-12-31
- Last updated by the study team
- 2026-02-25
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- out of hospital cardiac arrest (OHCA) patients
You may not qualify if…
- age <18 years
- non-EMS transport to the emergency department
- obvious signs of death (e.g. decapitation, rigor mortis, lividity, and decapitation) or having do-not-resuscitate (DNR) orders
- missing data despite meeting the inclusion criteria.
Where it is running
- National Taiwan University — Taipei, Taiwan (enrolling)
Full record on ClinicalTrials.gov
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