Short-term Clinical Outcome of Cortical Bone Trajectory Compared With the Traditional "Open" and Minimal Invasive Posterior Lumbar Interbody Fusion

Recruiting now

Conditions studied: Degenerative Spondylolisthesis, Spondylolytic Spondylolisthesis

In brief

A combined prospective cohort study and retrospective analysis of previously collected data. Three different techniques for posterior lumbar interbody fusion (PLIF) are compared: CBT-PLIF, MI-PLIF and open PLIF. A total of 180 patients are included, who will be followed up to 6 weeks postoperatively.

Key facts

Study ID

NCT05538416

Run by

Jos M. A. Kuijlen

People needed

180

Starts

2022-09-19

Expected to finish

2025-12-01

Last updated by the study team

2025-05-04

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18-75 years
• Degenerative or spondylolytic spondylolisthesis
• Neurogenic claudication and/or radicular leg pain
• Low grade (Meyerding grade l and ll)
• Persistent complaints for over 3 months

You may not qualify if…

• Previous spine fusion surgery at the same level
• Osteoporosis
• Active infection or prior infection at the surgical site
• Active cancer
• Spondylolisthesis grade lll or greater
• More than one symptomatic level that needs fusion
• Pregnancy
• Contraindication for surgery
• Severe mental or psychiatric disorder
• Substance abuse
• Inadequate knowledge of Dutch language
• Morbid obesity (body mass index >40)

Where it is running

• UMCG — Groningen, Netherlands (enrolling)

Full record on ClinicalTrials.gov

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