Racial/Ethnic in Calcium and Sodium Metabolism
Running, not enrolling · Not applicable
Conditions studied: Healthy
In brief
The increased interest in personalized nutrition has arisen because scientists are beginning to understand subgroup differences in response to the environment including diet. Some suggest that dietary guidance which promotes milk is racially and ethnically insensitive because of higher prevalence of lactose intolerance/maldigestion in non-white groups. Preliminary evidence in Black and White adolescent girls shows that Blacks retain more calcium and excrete more sodium than white girls on a high sodium diet making Whites more vulnerable to osteoporosis and Blacks more vulnerable to hypertension on high salt diets. Adequate dietary calcium is protective for both groups. This project will compare calcium absorption and calcium and sodium excretion from lactose-free milk as part of a controlled diet on higher (usual Western diet) and lower (recommended) salt intakes in Black, White, Hispanic, and Asian adults.
Key facts
- Study ID
- NCT05537857
- Run by
- San Diego State University
- People needed
- 66
- Starts
- 2023-03-01
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2026-07-31
Who can join
Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy adults age 18-50 years, but not postmenopausal
- 3 of 4 grandparents identified as one of four major racial/ethnic groups
- BMI between 18.5 and 30 AND waist circumference less than or equal to 88 cm for females and 102 cm for males
- No allergy to lactose-free milk.
You may not qualify if…
- Taking vasoactive or calcium metabolism-altering medications (statins, antihypertensives, aspirin, steroids, bisphosphonates, thiazide diuretics, hormone replacement therapy, and antidepressants)
- Had bone fracture within the past 6 months
- Diabetes
- Cance
- Liver disease
- Gastrointestinal disease (e.g.: Crohn's disease, irritable bowel syndrome, malabsorption syndrome)
- Decreased kidney function
- Smoking within the past 12 months before the study.
- Habitually consumption > 1000 mg Ca/d from food or supplements.
Where it is running
- San Diego State University — San Diego, California, United States
Full record on ClinicalTrials.gov
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