A RCT on the Preventive Effect of HFNC on Postoperative Pulmonary Complications in Patients With Gynecologic Neoplasms
Recruiting now · Not applicable
Conditions studied: Gynecologic Surgery, High-flow Nasal Cannula, Post-operative Pulmonary Complications
In brief
Patients at high risk of post-operative pulmonary complications (PPC) will be screened out from gynecological tumor patients undergoing surgical treatment, and randomly assigned into the HFNC group and control group, which uses conventional nasal cannula oxygen therapy. The primary outcome is the incidence of PPC, including postoperative hypoxemia, atelectasis, pneumonia, etc. Secondary outcomes are the improvement of postoperative oxygenation, antibiotic use, length of hospital stay, adverse events related to oxygen therapy, etc.
Key facts
- Study ID
- NCT05526534
- Run by
- Sichuan Cancer Hospital and Research Institute
- People needed
- 200
- Starts
- 2022-11-01
- Expected to finish
- 2025-12-31
- Last updated by the study team
- 2025-05-23
Who can join
Age: 18 and older, up to 90. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Patients with gynecologic Neoplasms, including benign gynecologic tumors and malignant gynecologic tumors, who are 18 to 90 years old and are scheduled for surgical treatment in our center shall receive plain chest CT scan within 1 week before surgery, and the estimated surgical time shall be ≥2 hours, and at least one of the following conditions shall be met:
- Assess respiratory risk in surgical patients in Catalonia (ARRSPC) ≥45 points;
- BMI≥30;
- Moderate to severe asthma;
- Moderate to severe chronic obstructive pulmonary disease (COPD);
- Smoking history ≥20 packs/year
You may not qualify if…
- Patients with lung metastasis of malignant tumor or primary lung malignant tumor;
- previous lung surgery or radiotherapy;
- the surgery involved segmental bowel resection.
Where it is running
- Sichuan Cancer Hospital and Research Institute — Chengdu, Sichuan, China (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.