The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial

Running, not enrolling · Not applicable

Conditions studied: Acute Respiratory Failure, Airway Extubation

In brief

The METEOR Trial will compare four implementation strategies-traditional online education, protocol-directed care, interprofessional education, and a combination of protocol-directed care and interprofessional education-to test the hypotheses that interprofessional education is superior to traditional online education as an implementation strategy in the intensive care unit (ICU) and the benefits of interprofessional education are increased when interprofessional education is paired with a clinical protocol. Additionally, the trial will also test the hypothesis that preventive post-extubation NIV for high-risk patients and preventive post-extubation HFNC for low-risk patients are both superior to current clinical practice (i.e., conventional post-extubation oxygen therapy).

Key facts

Study ID

NCT05523479

Run by

University of Pittsburgh

People needed

13018

Starts

2023-03-01

Expected to finish

2026-05-31

Last updated by the study team

2026-05-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All adults treated with invasive mechanical ventilation >24 hours in participating ICUs

You may not qualify if…

• None

Where it is running

• UPMC Carlisle — Carlisle, Pennsylvania, United States
• UPMC Hanover — Hanover, Pennsylvania, United States
• UPMC Harrisburg — Harrisburg, Pennsylvania, United States
• UPMC Community Osteopathic — Harrisburg, Pennsylvania, United States
• UPMC West Shore — Mechanicsburg, Pennsylvania, United States
• UPMC East — Monroeville, Pennsylvania, United States
• UPMC Jameson — New Castle, Pennsylvania, United States
• University of Pittsburgh — Pittsburgh, Pennsylvania, United States
• UPMC Magee-Womens Hospital — Pittsburgh, Pennsylvania, United States
• UPMC Presbyterian — Pittsburgh, Pennsylvania, United States
• UPMC St. Margaret — Pittsburgh, Pennsylvania, United States
• UPMC Mercy — Pittsburgh, Pennsylvania, United States
• UPMC Shadyside — Pittsburgh, Pennsylvania, United States
• UPMC Passavant — Pittsburgh, Pennsylvania, United States
• UPMC Northwest — Seneca, Pennsylvania, United States
• UPMC Williamsport — Williamsport, Pennsylvania, United States
• UPMC Memorial — York, Pennsylvania, United States

Full record on ClinicalTrials.gov

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