Reducing Blood Pressure in Mid-life Adult Binge Drinkers
Recruiting now · Not applicable
Conditions studied: Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence, Aging, Lifestyle Factors, Vasodilation, Behavioral Problem
In brief
This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers. Phase 2 is to examine the effect of 8-week aerobic exercise training on blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers
Key facts
- Study ID
- NCT05522075
- Run by
- The University of Texas at Arlington
- People needed
- 55
- Starts
- 2022-11-21
- Expected to finish
- 2027-04-30
- Last updated by the study team
- 2026-06-01
Who can join
Age: 50 and older, up to 64. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Men and women (50-64 years of age) who do not drink alcohol, who drink at moderate levels, or who binge drink
- Female subjects will be postmenopausal (i.e., cessation of menses for ≥1 yr).
- Subjects who can speak and understand English.
You may not qualify if…
- a history of diabetes, cardiovascular disease, liver, or renal disease
- current or history of smoking and illicit drug use
- blood pressure ≥160/100 mm Hg
- other known traditional cardiovascular disease risks: obesity (BMI≥35 kg/m2), or hyperlipidemia (total cholesterol>230 mg/dl and/or LDL cholesterol>160 mg/dl)
- active infection (in the past 2 months)
- a history of seizures, cancer, or inflammatory disease (i.e., gout or rheumatoid)
- unstable body weight (>5% change during the past 6 months)
- regular aerobic exercise training (i.e., they engage in 30 min of structured aerobic exercise at least 3 times per week)
- current use of hormone replacement therapy (i.e., estrogen, progesterone, and testosterone)
Where it is running
- University of Texas at Arlington — Arlington, Texas, United States (enrolling)
Full record on ClinicalTrials.gov
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