Neural Mechanisms of Obsessive-compulsive Disorder (OCD) Treatment Failure

Recruiting now

Conditions studied: Obsessive-Compulsive Disorder

In brief

The aim of this study is to understand why patients with obsessive-compulsive disorder (OCD) fail in therapy. To understand the neural mechanisms involved in exposure therapy that support success and clinical improvement in order to improve therapy outcomes for OCD patients.

Key facts

Study ID

NCT05520398

Run by

University College, London

People needed

90

Starts

2021-11-10

Expected to finish

2025-12-31

Last updated by the study team

2024-12-19

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of obsessive-compulsive disorder (OCD)
• Fluent in written and spoken English
• Normal/corrected to normal vision
• Expecting to start OCD therapy

You may not qualify if…

• Autism spectrum disorder, psychosis, schizophrenia, addiction, substance abuse, bipolar, hoarding, or Tourette disorder
• Hearing conditions: tinnitus, ear inflammation, hearing sensitivity, hearing loss, requires hearing aids
• Colour blindness
• Severe learning disabilities

Where it is running

• Max Planck UCL Centre for Computational Psychiatry and Ageing Research — London, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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