Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural

Enrolling by invitation

Conditions studied: Anesthesia, Analgesia

In brief

As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients. Prior studies have found epidural catheters placed via the combined-spinal epidural technique have greater success at surgical conversion for cesarean delivery than catheters placed via traditional techniques. The investigators aim to determine if epidural catheters placed by a DPE technique will also have an increased successful conversion for surgical anesthesia by conducting a retrospective review of all CD during the study period. If an association is found, this could be another benefit of DPE for labor analgesia.

Key facts

Study ID

NCT05514431

Run by

Mayo Clinic

People needed

1500

Starts

2017-02-01

Expected to finish

2026-07-01

Last updated by the study team

2025-08-17

Who can join

Age: any. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Women with neuraxial labor analgesia (CSE, DPE, or Epidural) who have an intrapartum cesarean delivery
• Singleton gestation

You may not qualify if…

• No local anesthetic given in epidural for cesarean delivery (in emergency situation)
• Inadvertent dural puncture

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States
• BC Women's Hospital — Vancouver, British Columbia, Canada

Full record on ClinicalTrials.gov

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