Exploring Central Sensitization in Pregnant Women
Recruiting now
Conditions studied: Pelvic Girdle Pain, Chronic Pain
In brief
Pelvic Girdle Pain (PGP) is reported by 50% of pregnant women and up to 11 years after pregnancy, 10% of women have persistent and per definition chronic PGP. Central (nervous system) sensitization that elicits pain hypersensitivity, may be one explanation. The overall aim of this study is to explore features of central sensitization in pregnant women and its predictive ability on physical activity, functioning and health in women with PGP. Measurements of central sensitization will be done on two study groups, pregnant women with PGP and healthy controls. To identify women at risk to develop chronic pain in relation to a common pain experience ie PGP in pregnancy, may help us understand if central sensitization early in life explains why women develop chronic pain.
Key facts
- Study ID
- NCT05507853
- Run by
- Göteborg University
- People needed
- 144
- Starts
- 2023-08-15
- Expected to finish
- 2025-12-31
- Last updated by the study team
- 2025-04-01
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- pregnant (first time pregnant or previous experience of pregnancy)
- 18 years of age or older
- have a single foetus pregnancy
- be in gestational weeks 20-30
- able to read and understand Swedish or English
You may not qualify if…
- no history of a fracture or malignant disease in the back, pelvis, pelvic floor or hips
- no systemic disease of the musculoskeletal or the nervous system
- no diseases such as gestational diabetes or diabetes type 1 and 2, hypertension
- no obstetric complications
- no contradiction for tests.
Where it is running
- Närhälsan Gibraltargatan — Gothenburg, Sweden (enrolling)
Full record on ClinicalTrials.gov
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