Temporal Window and Episodic Future Thinking in CUD

Completed · Not applicable

Conditions studied: Cocaine Use Disorder

In brief

The primary objective is to test the theory of Reinforcer Pathology via manipulation of the temporal window with successive Episodic Future Thinking generation in individuals with cocaine use disorder.

Key facts

Study ID

NCT05507814

Run by

Virginia Polytechnic Institute and State University

People needed

141

Starts

2022-11-30

Expected to finish

2025-11-24

Last updated by the study team

2025-12-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• demonstrate recent cocaine use and CUD (use in last month, DSM-5 for CUD > 4)
• be 18 years of age or older
• have a desire to quit or cut down on their cocaine use, but do not have proximate plans to enroll in treatment for CUD during the study period

You may not qualify if…

• meeting moderate to severe DSM-5 criteria for opioid use disorder
• having a current diagnosis of any psychotic disorder
• having a history of seizure disorders or traumatic brain injury
• having any contraindication for participation in the MRI sessions

Where it is running

• Fralin Biomedical Research Institute at VTC — Roanoke, Virginia, United States

Full record on ClinicalTrials.gov

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