Treating Pediatric NAFLD with Nutrition
Completed · Not applicable
Conditions studied: Non-Alcoholic Fatty Liver Disease, Liver Diseases, Liver Fat, Hepatic Steatosis, Nutritional and Metabolic Disease
In brief
This is a proof of concept clinical trial to compare daily intake of at least 20 grams of whole dairy fat vs habitual diet on hepatic steatosis in children with NAFLD.
Key facts
- Study ID
- NCT05499585
- Run by
- University of California, San Diego
- People needed
- 20
- Starts
- 2022-09-12
- Expected to finish
- 2024-09-10
- Last updated by the study team
- 2024-09-26
Who can join
Age: 10 and older, up to 17. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 10 through 17 years
- NAFLD
- ALT of ≥ 40 U/L
- MRI-PDFF ≥ 8%
- Ability and willingness of legal guardian and participant to provide written, informed consent
You may not qualify if…
- Competing Health Conditions
- Participants with a history of health issues that make it unsafe for them to participate in the opinion of the investigator
- Type 1 or Type 2 Diabetes
- LDL-cholesterol > 160 mg/dL
- Evidence of other chronic liver disease (alcohol liver disease, alcohol related liver disease, hepatitis C, chronic hepatotoxic drug use, mitochondrial diseases, autoimmune liver disease, wilson's disease)
- History of bariatric surgery or planning to undergo bariatric surgery during the study duration
- Participant with a history of conditions affecting digestion and/or absorption
- Intervention
- Inability or refusal to consume dairy
- Cow's milk protein allergy
- Lactose intolerance
Where it is running
- UC San Diego — La Jolla, California, United States
Full record on ClinicalTrials.gov
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