Use of Methazolamide to Lower Intraocular Pressure

Running, not enrolling · Phase 4

Conditions studied: Glaucoma, Open-Angle

In brief

The purpose of this study is to evaluate the effect of methazolamide, 25 mg or 50 mg tablets once a day for a week than twice a day for a week, on lowering intraocular pressure and the safety of methazolamide.

Key facts

Study ID

NCT05498103

Run by

University of Colorado, Denver

People needed

30

Starts

2023-02-17

Expected to finish

2024-12-01

Last updated by the study team

2024-02-06

Who can join

Age: 50 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males and females between 50 and 90 years old
• Current diagnosis of open angle glaucoma (OAG) in both eyes
• Ability to read and write in English

You may not qualify if…

• Glaucoma other than OAG
• Severe or end-stage glaucoma (cup to disc ratio >0.8 or Mean Deviation on Visual Field worse than -12)
• Pregnant or breast-feeding women

Where it is running

• Sue Anschutz-Rodgers Eye Center — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

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