A Study to Evaluate the Impact of Omeprazole on the Pharmacokinetics of Sotorasib Co-administered With an Acidic Beverage in Healthy Volunteers

Completed · Phase 1

Conditions studied: Healthy Volunteers

In brief

The primary objective of the study is to evaluate the effects of omeprazole (a proton-pump inhibitor) and an acidic beverage (Coca-Cola) on sotorasib pharmacokinetics (PK) when administered orally in healthy volunteers.

Key facts

Study ID
NCT05497557
Run by
Amgen
People needed
16
Starts
2022-07-14
Expected to finish
2022-09-08
Last updated by the study team
2024-01-19

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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