The Association of Transgelin-2, Metallothionein-2 and Ezrin With Asthma
Recruiting now
Conditions studied: Asthma
In brief
Asthma is one of the most common chronic respiratory diseases. Previous study found a series of differentially expressed genes and proteins (transgelin-2, metallothionein-2, ezrin) in asthmatic rat. The aim of the study is to investigate the changes and associations of these gene with asthma in human.
Key facts
- Study ID
- NCT05496582
- Run by
- Shanghai University of Traditional Chinese Medicine
- People needed
- 100
- Starts
- 2022-11-01
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2024-05-08
Who can join
Age: 14 and older, up to 75. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Males or females, aged 14-75 years;
- Patients with a definite diagnosis of bronchial asthma;
- The diagnosis of asthma according to the Global Initiative for Asthma (GINA), with positive bronchodilator responsiveness (reversibility) test;
- Healthy volunteers without respiratory symptoms such as cough, wheezing, chest tightness or dyspnea;
- Agree with all procedures in this trial by signing a written informed consent form.
You may not qualify if…
- Patients with chronic obstructive pulmonary disease or other airway disease;
- Complicated with other severe primary diseases (including hypertension, cancer, hyperthyroidism, bronchiectasia, cardiac insufficiency) and conditions that would prevent participation in the trial or put the participant at risk;
- Women who are known to be pregnant or breastfeeding;
- Not willing to participate;
- Psychiatric history and neurological disorders can not work normally;
- Other conditions that the researcher considers inappropriate to participate in this study.
Where it is running
- Xiangya Hospital, Central South University — Changsha, Hunan, China (enrolling)
- Yueyang Hospital, Shanghai University of Traditional Chinese Medicine — Shanghai, Shanghai Municipality, China
Full record on ClinicalTrials.gov
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