Factors Associated With an Evolution in the Quality of Life of Diabetic Patients With Chronic, Wound-free Charcot Foot
Recruiting now
Conditions studied: Charcot Joint of Foot, Osteoarthropathy
In brief
Charcot foot, characterized by progressive destructive damage to bone, soft tissue and tendons, involving joint dislocation in the ankle and foot, is a complication of diabetes that is still poorly understood by patients and caregivers. The clinical signs are non-specific and it is therefore largely underestimated due to a delay in diagnosis/lack of diagnosis.This study will be on a prospective multicenter cohort of patients with chronic Charcot's foot in France to evaluate the evolution of quality of life at 2 years, as well as predictive factors in order to better identify subjects with the worst outcome among this population. Our hypothesis is that, in patients with chronic Charcot foot, the deterioration in quality of life over time is primarily related to loss of foot and ankle functionality, foot and ankle deformity and the presence of foot wounds/comorbidities/severe diabetic complications.
Key facts
- Study ID
- NCT05491577
- Run by
- Centre Hospitalier Universitaire de Nīmes
- People needed
- 150
- Starts
- 2023-01-23
- Expected to finish
- 2028-01-22
- Last updated by the study team
- 2024-08-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- patients with Type 1 or 2 diabetes or secondary diabetes
- patient hospitalized or consulting for osteoarthropathy in its chronic stage, without wounds
- patients affiliated to or beneficiaries of a health insurance scheme.
- adult patients (≥18 years old).
You may not qualify if…
- patients with non-diabetic osteoarthropathy of the nerves.
- patients with acute diabetic osteoarthropathy of the nerves.
- patients with a foot ulcer
- patients who have expressed opposition to participating in the study.
- patients in an exclusion period determined by another study.
- patients under court protection, guardianship or trusteeship.
- patients for whom it is impossible to give informed information.
- pregnant, parturient, or breastfeeding patients.
Where it is running
- CHU de Montpellier Service des Maladies métaboliques 371 av. Doyen Giraud — Montpellier, France (enrolling)
- GH Pitié Salpétrière Unité de podologie Service de Diabétologie 47-83 Bd de l'Hôpital — Paris, France (enrolling)
- GH Paris Saint Joseph Service de Diabétologie et Endocrinologie 185 rue Raymond Losserand — Paris, France (enrolling)
- CHU Bicêtre Service d'Endocrinologie et Maladies de la reproduction 78 rue du Général Leclerc — Le Kremlin-Bicêtre, France (enrolling)
- CHU de Lyon Sud Service d'Endocrinologie-Diabète-Nutrition CH Lyon Sud Pavillon médical, Bat 1B 165 chemin du Grand Revoyet — Pierre-Bénite, France (enrolling)
- CHU Reims Service d'Endocrinologie, diabète-nutrition Rue du Général Koenig — Reims, France (enrolling)
- CH de Lens Unité de Diabétologie-Endocrinologie- Nutrition-Obésité Centre Hospitalier Dr SCHAFFNER 99 rte de La Bassée, — Lens, France (enrolling)
- Hôpital DRON Service de diabétologie 135 rue du Président Coty — Tourcoing, France (enrolling)
- Hôpitaux Universitaires de Strasbourg Service d'Endocrinologie et Diabétologie 1, place de l'hôpital, — Strasbourg, France
- CHU de la CONCEPTION Service de Nutrition, Diabétologie, Obésité médicale, chirurgicale 47 Bd Baille — Marseille, France
- Groupement Hospitalier Est, Hôpital Cardiologique Service de Diabétologie 28 Av du Doyen Lépine — Bron, France
- CH Sud Francilien Service de Diabétologie 40 Avenue Serge Dassault — Corbeil-Essonnes, France
- CHU de Grenoble Service d'Endocrinologie Allée des Sablons Les écrins — Grenoble, France
- Hôpital Hôtel dieu Service d'Endocrinologie 26 rue d'Harfleur — Le Creusot, France
- CHRU de Lille Service d'Endocrinologie Diabétologie et Métabolisme, Hôpital Claude Huriez, Rue Polonovski — Lille, France
- Centre Hospitalier de Boulogne-sur-Mer — Boulogne-sur-Mer, Pas-de-Calais, France
- Hôpital Cochin Service de diabétologie 123 Bd de Port Royal — Paris, France
Full record on ClinicalTrials.gov
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