Adapting and Evaluating a Tobacco Use Cessation Program for People Living With HIV in Uganda and Zambia

Recruiting now · Phase 1

Conditions studied: Nicotine Dependence, Tobacco Dependence

In brief

This proposal tests the efficacy of a phone-based tobacco cessation intervention for people living with HIV (PLWH) in comparison to the standard of care (brief advice to quit) and nicotine replacement therapy (nicotine patches) in Uganda and Zambia. This study will provide insight into the efficacy, feasibility, applicability, and affordability of delivering tobacco cessation interventions through health care professionals at HIV treatment centers in two countries with different tobacco use patterns, policy environments, and health care resources. The previously tested SMS-platform to be used in this study is uniquely positioned to be scaled in low- and middle-income countries worldwide, in which case rigorous research showing even modest success in reducing the prevalence of tobacco consumption among PLWH could confer substantial health and economic benefits.

Key facts

Study ID: NCT05487807
Run by: University of Southern California
People needed: 800
Starts: 2023-09-13
Expected to finish: 2026-08-31
Last updated by the study team: 2023-11-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

Females who are pregnant, planning to get pregnant, or breastfeeding
<18 years (underage of consent)
Visitor, not receiving continuous care at study site
Not a current daily tobacco user
Any physical, cognitive, or psychological disabilities that would prevent them from participating in the study
Illiterate in English and/or local languages
Does not consent

Where it is running

Makerere University — Kampala, Uganda (enrolling)
University of Zambia — Lusaka, Zambia (enrolling)

Full record on ClinicalTrials.gov

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