ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study

Enrolling by invitation · Phase 2

Conditions studied: Age Related Macular Degeneration (AMD)

In brief

The purpose of this study is to evaluate the long-term safety of GT005 in participants with Geographic Atrophy (GA) secondary to AMD who have been treated in an antecedent study.

Key facts

Study ID

NCT05481827

Run by

Gyroscope Therapeutics Limited

People needed

225

Starts

2022-07-12

Expected to finish

2028-06-02

Last updated by the study team

2024-03-22

Who can join

Age: 55 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Able and willing to give written informed consent
• Received GT005 in an antecedent study, GT005-01 (FOCUS, NCT03846193), GT005-02 (EXPLORE, NCT04437368) and GT005-03 (HORIZON, NCT04566445)
• Willing to attend study visits and complete the study procedures.

Where it is running

• Retina Consultants San Diego - Poway — Poway, California, United States
• Southwest Retina Research Center — Durango, Colorado, United States
• Vitreo Retinal Associates Pa - the Millennium Center Location — Gainesville, Florida, United States
• Rand Eye Institute, Inc. (Rei) — Pompano Beach, Florida, United States
• Retina Vitreous Associates of Florida — St. Petersburg, Florida, United States
• University Retina and Macula Associates, P.C. - Lemont Office — Lemont, Illinois, United States
• Midwest Eye Institute Northside — Indianapolis, Indiana, United States
• Wolfe Eye Clinic — West Des Moines, Iowa, United States
• The Retina Care Center, Llc - Baltimore Location — Baltimore, Maryland, United States
• Ophthalmic Consultants of Boston (OCB) — Boston, Massachusetts, United States
• Pepose Vision Institute, P.C - Midwest Vision Research Foundation — Chesterfield, Missouri, United States
• Sierra Eye Associates — Reno, Nevada, United States
• Columbia University Medical Center — New York, New York, United States
• Retina Associates of Western New York — Rochester, New York, United States
• Cincinnati Eye Institute — Cincinnati, Ohio, United States
• Sterling Vision - Oregon Retina, Llp — Eugene, Oregon, United States
• Mid Atlantic Retina - Wills Eye Hospital — Philadelphia, Pennsylvania, United States
• Retina Consultants of Austin — Austin, Texas, United States
• Texas Retina Associates (Tra) - Dallas Main — Dallas, Texas, United States
• Retina Consultants of Texas (Retina Consultants of Houston) - Texas Medical Center — Houston, Texas, United States
• Retina Consultants of Texas (Retina Consultants of Houston) - Texas Medical Center — Houston, Texas, United States
• Retinal Consultants of San Antonio (Rcsa) - Medical Center — San Antonio, Texas, United States
• The University of Melbourne - The Centre for Eye Research Australia (CERA) — Melbourne E., Victoria, Australia
• CHU Dijon - Hopital Mitterrand — Dijon, France
• CHU de Nantes - Hôtel-Dieu — Nantes, France

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.