Reward Circuit Targeted iTBS

Completed · Not applicable

Conditions studied: Transcranial Magnetic Stimulation

In brief

The objective of this study is to examine the effect of intermittent theta-burst transcranial magnetic stimulation (iTBS) targeting the reward circuit.

Key facts

Study ID

NCT05468853

Run by

Florida State University

People needed

72

Starts

2022-06-28

Expected to finish

2024-09-18

Last updated by the study team

2026-01-27

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Right-handed
• Native English speaker or fluent by the age of 6
• Elevated self-reported anhedonia

You may not qualify if…

• Left-handed
• Metal in head
• Brain tumor, stroke, aneurysm, multiple sclerosis
• Active substance use disorder in last 3 months
• Dementia or other cognitive disorder making unable to engage in treatment
• History or diagnosis of schizophrenia, schizoaffective disorder, delusional disorder, or other psychiatic illness that precludes safe participation in trial
• Suicidal risk that precludes safe participation
• obsessive-compulsive disorder
• Inability to stop taking any mediation that significant lowers the seizure threshold (e.g. tricyclic antidepressants, clozapine, etc.)
• Severe traumatic brain injury
• Non-English speaker

Where it is running

• FSU MRI Facility — Tallahassee, Florida, United States

Full record on ClinicalTrials.gov

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