Lung Nodule Detection Using Ultra-long FOV PET/CT

Recruiting now · Phase 4

Conditions studied: Lung Cancer

In brief

Indeterminate lung nodules (6-15mm) are frequent findings in patients undergoing chest CT scanning, but adequate follow-up imaging is currently not in place to facilitate early detection, diagnosis and decision making regarding treatment. The introduction of long Field-Of-View PET/CT scanners could make a difference in this matter due to the substantial increase in sensitivity allowing optimal image quality. Whether this new technology could provide improved detection and follow-up of indeterminate lung nodules is what we aim to explore in this study.

Key facts

Study ID

NCT05463913

Run by

University Medical Center Groningen

People needed

20

Starts

2022-07-13

Expected to finish

2025-06-01

Last updated by the study team

2025-03-07

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• able to give informed consent
• signed informed consent
• confirmed indeterminate lung nodule(s) of 6-15 mm in size on CT chest imaging
• routine 18F-FDG PET/CT performed
• scheduled for biopsy or resection of the lung nodules

You may not qualify if…

• claustrophobia
• pregnant or breastfeeding
• interval of at least 2 weeks between PET scan and last date of systemic anti-cancer therapy to reduce false-negative uptake in lesions
• radiation therapy of the target lung nodule(s)
• uncontrolled diabetes mellitus
• any medical condition potentially hampering conduction of the trial

Where it is running

• University Medical Center Groningen — Groningen, Netherlands (enrolling)

Full record on ClinicalTrials.gov

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