Scotoma Perimetry Oculomotor Training

Completed · Not applicable

Conditions studied: Macular Degeneration, Central Visual Impairment

In brief

The proposed research is relevant to public health because a greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the NEI to support research on visual disorders, mechanisms of visual function and preservation of sight. Declines in vision are particularly common in older adults and thus increasing our understanding of how to cre- ate effective means of improving vision is also highly relevant to the mission of the NIA to support research on aging and the health and well-being of older people.

Key facts

Study ID

NCT05456581

Run by

University of Alabama at Birmingham

People needed

21

Starts

2022-11-01

Expected to finish

2025-06-30

Last updated by the study team

2025-10-24

Who can join

Age: 18 and older, up to 89. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Severely impaired vision in both eyes (20/100 or worse)
• Diagnosis of Macular Degeneration
• Light sensitivity in the macular retina that is at least 10 dB units worse than in peripheral regions, as demonstrated by a scanning laser ophthalmoscope (SLO, MAIA)
• Medical record review indicates this disease severity level has been present for at least 2 years.

You may not qualify if…

• Inability to sit still in eye tracker for extended periods
• Inability to visualize iris on video eye tracker
• Bilateral retinal scotomas larger than 20° diameter

Where it is running

• UAB — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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