Factors in Learning And Plasticity: Macular Degeneration
Recruiting now · Not applicable
Conditions studied: Central Visual Impairment, Macular Degeneration
In brief
A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the NEI to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the NIMH RDOC framework and studies in an aging population are consistent with the mission of the NIA.
Key facts
- Study ID
- NCT05454124
- Run by
- University of Alabama at Birmingham
- People needed
- 60
- Starts
- 2022-11-01
- Expected to finish
- 2026-11-01
- Last updated by the study team
- 2026-02-09
Who can join
Age: 18 and older, up to 89. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Aged 18-89
- Severely impaired vision in both eyes (20/100 or worse)
- diagnosis of Macular Degeneration by an Ophthalmologist
- Light sensitivity in the macular retina that is at least 10 dB units worse than in peripheral regions, as demonstrated by a scanning laser ophthalmoscope (MAIA)
- Medical record review indicating this level of disease severity has been present for at least 2 years
- Reside within 50 miles of study site
You may not qualify if…
- Pacemaker or any ferromagnetic metal implanted in their body
- Metal of any type implanted in their head (limited dental work is acceptable)
- Claustrophobia
- Being hearing-impaired
- Weight over 300 pounds
- Maximum body girth over 60 inches
- Previous serious head injury
- Presence of hallucinations or delusions
- Excessive old, or colorful tattoos, especially near the head
- Pregnancy
- Braces/permanent retainer
Where it is running
- UAB — Birmingham, Alabama, United States (enrolling)
Full record on ClinicalTrials.gov
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