Filter Lifespan in Continuous Renal Replacement Therapy
Recruiting now
Conditions studied: Critically Ill, Continuous Renal Replacement Therapy, Infections
In brief
The only supportive therapy for patients with AKI is renal replacement therapy (RRT). In the ICU setting, continuous RRT (CRRT) is mostly favored. In a post-hoc analysis of the RICH trial (regional citrate versus systemic heparin anticoagulation for CRRT in critically ill patient with AKI), it was shown that the filter life span is associated with an increased rate of new infection and that the type of anticoagulants did not directly affect infection rate. The mechanisms of this infection rate is unknown.
Key facts
- Study ID
- NCT05450185
- Run by
- University Hospital Muenster
- People needed
- 600
- Starts
- 2023-03-02
- Expected to finish
- 2025-08-01
- Last updated by the study team
- 2024-12-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult patients (age ≥18 years)
- Critically ill patients with dialysis-dependent AKI
- Continuous renal replacement therapy (CRRT)
- Written informed consent
You may not qualify if…
- Chronic kidney disease with estimated glomerular filtration rate (eGFR)<30ml/min/1.73m2
- Chronic dialysis dependency
- Kidney transplant
- (Glomerulo-)nephritis, interstitial nephritis, vasculitis
- Patients on immunosuppression
- Patients with chronic inflammatory diseases (e.g. arthritis, HIV, chronic hepatitis)
- Persons with any kind of dependency on the investigator or employed by the sponsor or investigator
Where it is running
- Univ.-Klinik Innsbruck — Innsbruck, Austria (enrolling)
- Universidade de São Paulo — São Paulo, Brazil (enrolling)
- Universitätsklinikum Erlangen-Nürnberg, Abteilung für Nephrologie und Hypertensiologie — Erlangen, Germany (enrolling)
- Kliniken Maria Hilf, Klinik für Anästhesiologie und Operative Intensivmedizin — Mönchengladbach, Germany (enrolling)
- University Hospital Muenster — Münster, Germany (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.