Adenoma Detection Rate in Water and Air Colonoscopy Using Computer-aided System
Status unconfirmed · Not applicable
Conditions studied: Colon Adenoma, Colonoscopy
In brief
Water exchange (WE) is an effective insertion method to minimize insertion discomfort and maximize ADR. It is characterized by infusing water to guide insertion in an airless lumen with suctioning of infused water during insertion and almost complete removal of the infused water when cecal intubation is achieved. A modified Delphi review reported water exchange showed the highest overall ADR, ADR in screening cases, and in the right side of the colon compared with water immersion and air (or CO2) insufflation. One of the plausible mechanisms of improving ADR by water exchange is salvage cleaning during insertion, which might help artificial intelligence by removing the interference of fecal debris and bubbles. However, no RCT has been performed to evaluate the effect of CADe on WE colonoscopy. Therefore, investigators will conduct a RCT comparing the ADR of CADe assisted colonoscopy inserted with either WE or insufflation. Our hypothesis will be that CADe assisted WE colonoscopy achieves higher ADR than CADe assisted air insufflation colonoscopy.
Key facts
- Study ID
- NCT05448300
- Run by
- Dalin Tzu Chi General Hospital
- People needed
- 250
- Starts
- 2022-05-16
- Expected to finish
- 2023-05-15
- Last updated by the study team
- 2022-07-12
Who can join
Age: 50 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Consecutive patients, undergoing screen, diagnostic or surveillance colonoscopy performed by the participating endoscopists will be enrolled.
You may not qualify if…
- We excluded patients age < 50 or > 80 years old, undergone colonoscopy in the past 3 years, partial intake of bowel preparation, renal failure, previous colonic resection, scheduled for polypectomy, American Society of Anesthesiology (ASA) Risk Class 3 or higher, and lack of written informed consent.
Where it is running
- Chia Pei Tang — Chiayi City, Chiayi County, Taiwan (enrolling)
- Sepulveda Ambulatory Care Center — Los Angeles, California, United States
Full record on ClinicalTrials.gov
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