Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age
Recruiting now · Phase 4 · Has a placebo group
Conditions studied: Bronchiolitis Acute Viral
In brief
The aim of the trial is to evaluate whether the use of oral prednisolone directed by point-of-care testing is useful in acute wheezing caused by rhinovirus in children aged 6-24 months.
Key facts
- Study ID
- NCT05444699
- Run by
- University of Oulu
- People needed
- 210
- Starts
- 2022-10-11
- Expected to finish
- 2027-09-01
- Last updated by the study team
- 2025-02-13
Who can join
Age: 1 and older, up to 2. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Wheezing bronchitis diagnosed by a physician
- Need for salbutamol treatment at the emergency department
- Positive nasopharyngeal rhinovirus or picornavirus finding in point-of-care testing
You may not qualify if…
- Need for immediate resuscitation
- Immediate transfer to ICU
- Suspected pneumonia based on the auscultation finding
- Suspected serious bacterial infection
- Other respiratory virus finding in the absence of rhinovirus or picornavirus
- Positive respiratory syncytial virus finding
- Positive SARS-coronavirus-2 finding
- Positive Mycoplasma pneumoniae finding
- Positive Bordetella pertussis finding
- Contact with a person with chickenpox within 14 days
- Active chickenpox
- Suspected foreign body of the respiratory tract
- Immunosuppressive treatment
- Systemic corticosteroid treatment within 14 days
- Allergy to corticosteroids
Where it is running
- SOITE Lastenpäivystys — Kokkola, Finland (enrolling)
- OYS Lastenpäivystys — Oulu, Finland (enrolling)
Full record on ClinicalTrials.gov
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