Activity, Adiposity, and Appetite in Adolescents 2 Intervention
Completed · Not applicable
Conditions studied: Obesity, Energy Balance, Appetite, Metabolism, Insulin Sensitivity
In brief
The objective of the study is to quantify the relationship between physical activity, metabolic function, and appetite in adolescents. To do this we will test our working hypothesis that high levels of regular moderate-to-vigorous physical activity (MVPA), as opposed to body weight status, results in a metabolic phenotype consisting of enhanced metabolic function and proper regulation of appetite. We will randomly assigning sedentary overweight/obese adolescents (N=44) to either a control or structured-exercise group for three months.
Key facts
- Study ID
- NCT05443347
- Run by
- Children's Mercy Hospital Kansas City
- People needed
- 31
- Starts
- 2022-09-14
- Expected to finish
- 2024-11-25
- Last updated by the study team
- 2026-02-12
Who can join
Age: 14 and older, up to 17. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Tanner Stage III-V, as determined via self-assessment
- Non-smoking
- Not currently involved in any other research study
- No meds that may alter metabolism
- Sedentary (<60 min/day exercise)
- Willing to participate in an exercise program
You may not qualify if…
- BMI <5th percentile or >99th percentile for age and sex
- Weight not stable
- Restrained eater (>13 on the restraint section of the three-factor eating questionnaire; Current/past diagnosis of an eating disorder.
- Self-reported medical conditions (including, but not limited to, diabetes, Crohn's disease, etc.) that may affect adherence to the protocol, exercising safely, or alter metabolism
- Taking medications know to affect metabolism (e.g. thyroid medication, β-blockers, or stimulants).
- Gave birth in the past 12 months or <6 months post-lactation.
- Active (>60 min/day exercise)
- Not willing to participate in an exercise program
Where it is running
- Children's Mercy Kansas City — Kansas City, Missouri, United States
Full record on ClinicalTrials.gov
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