Factors in Learning And Plasticity: Healthy Vision

Running, not enrolling · Not applicable

Conditions studied: Central Visual Impairment, Macular Degeneration

In brief

A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the National Eye Institute (NEI) to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the National Institute of Mental Health (NIMH) Research Domain Criteria (RDOC) framework and studies in an aging population are consistent with the mission of the National Institute on Aging (NIA).

Key facts

Study ID

NCT05439759

Run by

University of Alabama at Birmingham

People needed

120

Starts

2022-10-24

Expected to finish

2026-11-01

Last updated by the study team

2026-02-09

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aged 18-30
• Corrected vision (20/40 or better)
• No reported incidence of retinal pathology.

You may not qualify if…

• Pacemaker or any ferromagnetic metal implanted in their body
• Metal of any type implanted in their head (limited dental work is acceptable)
• Claustrophobia
• Needing non-standard glasses (other than the simple MR-compatible glasses that can be supplied) for best-corrected distance vision
• Being hearing-impaired
• Weight over 300 pounds
• Maximum body girth over 60 inches
• Previous serious head injury
• Presence of hallucinations or delusions
• Excessive old, or colorful tattoos, especially near the head
• Pregnancy
• Braces/permanent retainer

Where it is running

• UAB — Birmingham, Alabama, United States
• University of California, Riverside — Riverside, California, United States

Full record on ClinicalTrials.gov

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