Joint Health Study
Status unconfirmed · Not applicable · Has a placebo group
Conditions studied: Effect of Drug
In brief
Natural dietary health supplements that may improve quality of life by relieving joint discomfort have been of increasing interest. Recent studies have demonstrated promising effects of one such supplement - calcium fructoborate (CFB). Preliminary evidence suggests that CFB may reduce joint discomfort, however, few well-powered studies have been conducted to assess the true effects of this supplement. In this study, conducted virtually, we will examine changes in joint discomfort over a 90 day period. Participants will be randomized to receive either 216mg CFB or placebo (i.e., 216mg microcellulose) to take every day for the study period.
Key facts
- Study ID
- NCT05438979
- Run by
- Auburn University
- People needed
- 300
- Starts
- 2022-07-01
- Expected to finish
- 2024-12-31
- Last updated by the study team
- 2023-08-16
Who can join
Age: 40 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Between 40-65 years of age;
- Self-reported or medically diagnosed knee joint pain for > 3 months (chronic);
- Diagnosis of osteoarthritis of the knee;
- No diagnosed psychiatric or neurological condition;
- Not taking antibiotics;
- Not taking any other joint health supplement
- Not taking prescription medications for OA or joint discomfort for the last 3 months
- No use of NSAIDS or other pain relievers for two (2) weeks prior to enrollment in the study and who are willing to make best efforts to refrain from use of same throughout the study
- Has reliable internet service;
- Some computer literacy;
- Has a smartphone; and
- Has a laptop, desktop computer, or iPad.
You may not qualify if…
- <40 or >65 years of age;
- Does not have osteoarthritis of the knee;
- Diabetes or other metabolic disorders;
- Inflammatory and/or infectious health conditions;
- Participants medically diagnosed with rheumatoid arthritis; 7) Participants with cardiovascular diseases; 8) Participants with liver and/or kidney problems; 9) Participants who are pregnant; 10) Health conditions that would prevent the participant from successfully completing the study (i.e., motor control conditions such as Parkinson's; psychiatric conditions such as ADHD); 11) Use of antibiotics 1 month prior to the enrollment in the study; 12) Physician prescribed use of pharmaceutical medications for OA or joint discomfort within 3 months prior to enrollment in this study; 13) Any joint injury in the 6-months prior to the enrollment in the clinical trial; 14) Unreliable or no internet access/service; 15) Unable to use a smartphone or lacking the computer literacy needed to complete the study 16) No laptop, desktop, or iPad that would allow for the completion of the study tasks.
Where it is running
- Auburn University — Auburn, Alabama, United States (enrolling)
Full record on ClinicalTrials.gov
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