Non-Invasive Mapping of Cerebral Autoregulation Using Near Infrared Spectroscopy

Recruiting now · Not applicable

Conditions studied: Cerebral Autoregulation Mapping

In brief

The investigators propose to employ advanced multi-channel near non-invasive near infrared spectroscopy (NIRS) system married with entirely non-invasive continuous arterial blood pressure (niABP) monitor to create a new wearable and portable imaging system that derives CA maps of the entire brain with high sampling rates at each point. The objectives of this project are as follows: 1. To perform in vivo testing and optimization of the device using a block-trial design to evaluate the CA mapping system's performance during various perturbations. 2. To explore the impact of aging and sex on regional disparities in CA in a healthy volunteer population using static recording along with perturbation testing.

Key facts

Study ID

NCT05433129

Run by

University of Manitoba

People needed

250

Starts

2023-07-11

Expected to finish

2027-12-31

Last updated by the study team

2026-01-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy volunteers (male and female)
• Age > 17

You may not qualify if…

• History of neurological illness
• History of systemic vascular
• History of cerebrovascular disease

Where it is running

• Health Sciences Centre (HSC) — Winnipeg, Manitoba, Canada (enrolling)

Full record on ClinicalTrials.gov

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