Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) International Registry
Recruiting now
Conditions studied: Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
In brief
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a very rare hematologic malignancy. Despite recent advances, at present there is no consensus on the optimal treatment of BPDCN. The optimal therapy of disease remains to be determined, and due to the rarity of cases, there is a need for international collaboration to collect data on BPDCN clinical presentations, diagnostics, treatment regimens and outcomes. Therefore, the objectives of this study are: (1) to build a large database of patients with BPDCN, (2) to investigate the characteristics and outcome of the disease with different treatment regimens, (3) to evaluate prognostic factors, and (4) to generate data-based prospective treatment recommendations.
Key facts
- Study ID
- NCT05430971
- Run by
- Immune Oncology Research Institute
- People needed
- 200
- Starts
- 2022-07-01
- Expected to finish
- 2032-07-01
- Last updated by the study team
- 2026-06-05
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of BPDCN
- Signed informed consent form for prospective patients
Where it is running
- Sylvester Comprehensive Cancer Center, University of Miami — Miami, Florida, United States (enrolling)
- Moffitt Cancer Center — Tampa, Florida, United States (enrolling)
- Seattle Children's Cancer and Blood Disorders Center — Seattle, Washington, United States (enrolling)
- Hematology Center named after prof. R. Yeolyan — Yerevan, Armenia (enrolling)
- University of Calgary — Calgary, Alberta, Canada (enrolling)
- Children's Hospital of Eastern Ontario, University of Ottawa — Ottawa, Ontario, Canada (enrolling)
- Cyprus Society of Haematology — Nicosia, Cyprus (enrolling)
- Oncology Center, Mansoura University Faculty of Medicine — Al Mansurah, Egypt (enrolling)
- M. Iashvili Children's Central Hospital — Tbilisi, Georgia (enrolling)
- Department of Medical Oncology, Dr. B.R.A Institute Rotary Cancer Hospital, All India Institute of Medical Sciences — New Delhi, India (enrolling)
- Pediatric Hematology Oncology, Children's Welfare Teaching Hospital, Medical City, College of Medicine, University of Baghdad — Baghdad, Iraq (enrolling)
- University of Perugia - Azienda Ospedaliera Perugia — Perugia, Italy (enrolling)
- Department of Biomedicine and Prevention, University of Rome Tor Vergata — Roma, Italy (enrolling)
- King Hussein Cancer Center (KHCC) — Amman, Jordan (enrolling)
- Department of hematology, Kuwait Cancer Control Center — Kuwait City, Kuwait (enrolling)
- Fundeni Clinical Institute, Department of Acute Leukemia — Bucharest, Romania (enrolling)
- China Medical University Children's Hospital — Taichung, Taiwan (enrolling)
- Turkish Pediatric Cancer Registry — Ankara, Turkey (Türkiye) (enrolling)
- Istanbul University, Oncology Institute — Istanbul, Turkey (Türkiye) (enrolling)
- University of Health Sciences, Umraniye Research and Education Hospital, Pediatric Hematology and Oncology Department, Pediatric Bone Marrow Transplantation Unit — Istanbul, Turkey (Türkiye) (enrolling)
- Broomfield Hospital, Haematology Mid and South Essex University Hospitals Group — Chelmsford, Essex, United Kingdom (enrolling)
- United Lincolnshire Teaching Hospital NHS Trust — Lincoln, Lincolnshire, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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