A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors

Running, not enrolling · Not applicable

Conditions studied: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Lymphoblastic Lymphoma

In brief

This clinical trial evaluates a high intensity electronic health (eHealth) intervention program for reducing learning disparities in children with cancer. Most children with leukemia and lymphoblastic lymphoma can be cured due to advancements in diagnosis and treatment. However, because treatments for these conditions target the central nervous system, these children are at increased risk for developing neurocognitive late effects (problems with attention, thinking, learning, and remembering). Fortunately, many survivors do well, but some children continue to struggle with learning and have academic difficulties after their cancer treatments. The purpose of this research study is to see whether providing parents with educational knowledge and parenting tips using videoconferencing and a special website better helps their cancer survivor child in learning and school achievement compared to typical services.

Key facts

Study ID

NCT05428176

Run by

City of Hope Medical Center

People needed

332

Starts

2023-02-16

Expected to finish

2027-06-30

Last updated by the study team

2026-06-04

Who can join

Age: 6 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Documented informed consent of the participant and/or legally authorized representative
• Assent, when appropriate, will be obtained per institutional guidelines
• Primary participating parent/caregiver is English- or Spanish-speaking (any race/ethnicity)
• Child is aged 6-12 years (yr.) (for the website usability pre-study, child is age 8 - 12 yrs.)
• Child understands English (but can be bilingual)
• Child treated for acute leukemia (e.g., acute lymphoblastic leukemia, acute myelogenous leukemia) or lymphoblastic lymphoma
• Child is in cancer remission and has completed cancer therapies, including maintenance treatment
• Primary participating parent/caregiver has daily contact with the child
• Child is enrolled in school

You may not qualify if…

• Recent or current participation in a behavioral intervention study with a similar focus
• History of major psychiatric condition (e.g., psychosis) in parent or child
• Severe neurodevelopmental disorder in the child (e.g., down syndrome, intellectual disability)
• Child has previously used the IXL online learning program extensively and unwilling to regularly use it again
• Any other condition that would, in the investigator's judgment, contraindicate the patient's participation in the clinical study due to safety concerns with clinical study procedures
• Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including compliance issues related to feasibility/logistics)

Where it is running

• City of Hope Medical Center — Duarte, California, United States
• Childrens Hospital of Los Angeles — Los Angeles, California, United States
• Rady Children's Hospital San Diego — San Diego, California, United States
• University of Calif San Francisco — San Francisco, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.