Early Pulmonary Dysfunction in Childhood Cancer Patients
Recruiting now
Conditions studied: Pulmonary Dysfunction
In brief
This longitudinal, prospective, multicentre study is to monitor lung function prospectively in childhood cancer patients after diagnosis. The impact of cancer treatment on pulmonary dysfunction non-invasively using lung function, lung imaging and breath analysis as well as clinical symptoms using a questionnaire will be assessed at different time points.
Key facts
- Study ID
- NCT05427136
- Run by
- University Children's Hospital Basel
- People needed
- 140
- Starts
- 2021-06-01
- Expected to finish
- 2051-06-01
- Last updated by the study team
- 2026-05-08
Who can join
Age: 4 and older, up to 22. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- at least one of the following cancer treatments:
- chest radiation
- treatment with any kind of chemotherapy
- hematopoietic stem cell transplantation (HSCT)
- thoracic surgery
- consent for Childhood Cancer Registry (ChCR) registration
You may not qualify if…
- no signed informed consent
- Operation outside the chest area as only cancer treatment
- Relapsed cancer (patients who develop relapse during the study will not be excluded)
- In addition for MRI and lung function tests:
- Subjects who are respiratory insufficient and cannot perform a lung function test (less than 92% O2 saturation; under O2 therapy)
- Pregnant
- MRI measurement not possible without sedation
- Metal (e.g. pacemaker) in the body
Where it is running
- University Children's Hospital Basel (UKBB) — Basel, Switzerland (enrolling)
- Universitätsklinik für Kinderheilkunde — Bern, Switzerland (enrolling)
- Geneva University Hospital — Geneva, Switzerland (enrolling)
- Centre hospitalier universitaire vaudois Lausanne — Lausanne, Switzerland (enrolling)
- Universitäts-Kinderspital Zürich — Zurich, Switzerland (enrolling)
Full record on ClinicalTrials.gov
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